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Phospholipids

How is the acid mantle made? The acid is produced when enzymes break down fat-like molecules in skin cells, called phospholipids, into smaller acid-tipped fat molecules called fatty acids; i.e., the skin generates the acid as it converts phospholipids into fatty acids.

Phospholipids are a class of lipids and are a major component of all cell membranes.

Phosphatidylcholines are a class of phospholipids which incorporate choline as a headgroup. Phosphatidylcholines are such a major component of lecithin.

Data suggest that of the two main essential fatty acids that occur in skin, linoleic acid and arachidonic acid, the former specifically plays an important role in regulating barrier function whereas the latter may have a separate function, such as serving as a precursor of prostaglandins.

Lecithin consists of Choline, Inositol, Linoleic Acid and has been used as a fat emulsifier for proper brain function, proper nerve function, and maintaining proper electrical energy and nutrients transfer across the cell membranes. Lecithin is another name for Phosphatidylcholine, one of the Phospholipids. Phospholipids (phosphatides) are indispensable components of cell membranes and are also natural emulsifiers, helping fats dissolve in water.

Phosphatidic acid (PA) is the acid form of phosphatidate, a common phospholipid that is a major constituent ofcell membranes. Phosphatidate acid is the smallest of the phospholipids.  A signalling lipid.

Reduced conversion of linoleic acid to its metabolites and reduced rate of incorporation of essential fatty acids ("EFAs") into phospholipids leads to a reduced formation of prostaglandin E1 (PGE1) which in turn leads to lower concentrations of cyclic AMP and to a selective hyperactivity of parts of the immune system. 

[Analysis of immunosuppressive activity of lecithin-bound iodine (LBI) on antigen-induced IL2 responsiveness in peripheral blood lymphocytes from patients with allergic diseases]http://www.biomedexperts.com/Abstract.bme/8279971/Analysis_of_immunosuppressive_activity_of_lecithin-bound_iodine_LBI_on_antigen-induced_IL2_responsiveness_in_peripher Taken together, LBI could work as a weak immunosuppressant to inhibit lymphocyte responses to allergen and to improve clinical status in allergic diseases, including bronchial asthma caused by Df and atopic dermatitis provoked by OVA